Publications

C. Seton, A. Coutrot, M. Hornberger, H J. Spiers, R. Knight, C Whyatt. (March 9, 2026). Wayfinding and path integration deficits detected using a virtual reality mobile app in patients with traumatic brain injury. PLoS ONE 18(3)

T Zaksaite, C Loveday, T Edginton, HJ Spiers, AD Smith. (2023). Hydrocephalus: A neuropsychological and theoretical primer. Cortex, Volume 160, Pages 67-99.

PS Muhle-Karbe, H Sheahan, G Pezzulo, HJ Spiers, S Chien, NW Schuck, C Summerfield. (Feb 2023). Goal-seeking compresses neural codes for space in the human hippocampus and orbitofrontal cortex. Biorxiv preprint.

R Dalton, J Wiener, D Yesiltepe, A Adams, N Dalton, H Spiers, M Hornberger. (Feb 2023). Motivational Factors for Participating in Citizen Science Games. Northumbria Research Link.

Greg L. West, Zita Eva Patai, Antoine Coutrot, Michael Hornberger, Véronique D. Bohbot, & Hugo J. Spiers. (2023). Landmark-dependent Navigation Strategy Declines across the Human Life-Span: Evidence from Over 37,000 Participants. Journal of Cognitive Neuroscience, 1–16, 35 (3): 452–467.

A. Coutrot, A. S. Lazar, M. Richards, E. Manley, J. M. Wiener, R. C. Dalton, M. Hornberger & H. J. Spiers. (2022). Reported sleep duration reveals segmentation of the adult life-course into three phases. Nature Communications, 13, 7697.

 

Brunec, I. K., Robin, J., Patai, E. Z., Ozubko, J. D., Javadi, A., Barense, M. D., Spiers, H. J, & Moscovitch, M. (2019). Cognitive mapping style relates to posterior–anterior hippocampal volume ratio. Hippocampus

 

 

 

 

Javadi, A., Patai, E. Z., Marin-Garcia, E., Margolis, A., Tan, H. M., Kumaran, D., ... & Spiers, H. J. (2019). Prefrontal dynamics associated with efficient detours and shortcuts: a combined fMRI and MEG study. Journal of Cognitive Neuroscience

 

Coughlan, G., Coutrot, A., Khondoker, M., Minihane, A. M., Spiers, H. J., & Hornberger, M. (2019). Big data in spatial navigation–towards personalised cognitive diagnostics of ‘at-genetic-risk’Alzheimer’s disease. PNAS

Coutrot, A., Schmidt, S., Coutrot, L., Pittman, J., Hong, L., Wiener, J. M., ... & Spiers, H. J. (2019). Virtual navigation tested on a mobile app is predictive of real-world wayfinding navigation performance. PloS one

Patai, E. Z., Javadi, A. H., Ozubko, J. D., O’Callaghan, A., Ji, S., Robin, J., ... & Spiers, H. J. (2019). Hippocampal and Retrosplenial Goal Distance Coding After Long-term Consolidation of a Real-World Environment. Cerebral Cortex



Brunec, I. K., Robin, J., Patai, E. Z., Ozubko, J. D., Javadi, A. H., Barense, M. D., Spiers, H. J., & Moscovitch, M. (2019). Cognitive mapping style relates to posterior–anterior hippocampal volume ratio. Hippocampus

Coutrot, A., Silva, R., Manley, E., de Cothi, W., Sami, S., Bohbot, V., Wiener, J. M., Hölscher, C., Dalton, R. C., Hornberger, M., Spiers, H. J. (2018). Global determinants of navigation ability. Current Biology

Spiers, H. J., Olafsdottir, H. F., & Lever, C. (2018). Hippocampal CA1 activity correlated with the distance to the goal and navigation performance. Hippocampus. 



Ekstrom, A. D., Spiers, H. J., Bohbot, V. D., & Rosenbaum, R. S. (2018). Human Spatial Navigation. Princeton University Press



Coughlan, E., Flanahan, E., Jeffs, S., Bertoux, M., Spiers, H. J., Moishi, E., & Hornsberger, M. (2018). Diagnostic relevance of spatial orientation for vascular dementia: A case study. Dimentia & neuropsychologia



Cialone, C., Tenbrink, T., & Spiers, H. J. (2018). Sculptors, Architects, and Painters Conceive of Depicted Spaces Differently. Cognitive science



Javadi, A. H., Patai, E. Z., Marin-Garcia, E., Margois, A., Tan, H., Kumara, D., Nardini, M., Penny, W., Duzel, E., Dayan, P., & Spiers, H. J. (2018). Human back-tracking behaviour is associated with suppression of default-mode region activity and enhanced dorsal anterior cingulate activity. bioRxiv



Epstein, R. A., Patai, E. Z., Julian, J. B., & Spiers, H. J. (2017). The cognitive map in humans: spatial navigation and beyond. Nature neuroscience

Javadi, A. H., Glen, J. C., Halkiopoulos, S., Schulz, M., & Spiers, H. J. (2017). Oscillatory Reinstatement Enhances Declarative Memory. Journal of Neuroscience



Brunec, I. K., Javadi, A. H., Zisch, E. L., & Spiers, H. J. (2017). Contracted time and expanded space: The impact of circumnavigation on judgements of space and time
. Cognition



Patai, E. Z., & Spiers, H. J. (2017). Human navigation: occipital place area detects potential paths in a scene. Current Biology



Javadi, A. H., Emo, B., Howard, L. R., Zisch, F. E., Yu, Y., Knight, R., ... & Spiers, H. J. (2017). Hippocampal and prefrontal processing of network topology to simulate the future. Nature communications



de Cothi, W., & Spiers, H. J. (2017). Spatial cognition: Goal-vector cells in the bat hippocampus. Current Biology 



Spiers, H. J., Love, B. C., Le Pelley, M. E., Gibb, C. E., & Murphy, R. A. (2017). Anterior temporal lobe tracks the formation of prejudice. Journal of cognitive neuroscience


Patai, E. Z., Javadi, A. H., Ozubko, J. D., O'Callaghan, A., Ji, S., Robin, J., ... & Spiers, H. J. (2017). Long-term consolidation switches goal proximity coding from hippocampus to retrosplenial cortex. bioRxiv


Tu, S., Spiers, H. J., Hodges, J. R., Piguet, O., & Hornberger, M. (2017). Egocentric versus allocentric spatial memory in behavioral variant frontotemporal dementia and Alzheimer’s disease. Journal of Alzheimer's Disease



Spiers, H. J., de Cothi, W., & Bendor, D. (2017). Manipulating Hippocampus-Dependent Memories: To Enhance, Delete or Incept?. In The hippocampus from cells to systems, Springer



Patai, E. Z., & Spiers, H. J. (2017). Cracking the mnemonic code. Nature neuroscience 



Jafarpour, A., & Spiers, H. (2017). Familiarity expands space and contracts time. Hippocampus 



Chadwick, M. J., Anjum, R. S., Kumaran, D., Schacter, D. L., Spiers, H. J., & Hassabis, D. (2016). Semantic representations in the temporal pole predict false memories. Proceedings of the National Academy of Sciences



Balaguer, J., Spiers, H., Hassabis, D., & Summerfield, C. (2016). Neural mechanisms of hierarchical planning in a virtual subway network. Neuron



Spiers, H. J. (2016). Spatial cognition: finding the boundary in the occipital place area. Current Biology


Bendor, D., & Spiers, H. J. (2016). Does the hippocampus map out the future?  Trends in cognitive sciences



Javadi, A. H., Tolat, A., & Spiers, H. J. (2015). Sleep enhances a spatially mediated generalization of learned values.  Learning & Memory


Ólafsdóttir, H. F., Barry, C., Saleem, A. B., Hassabis, D., & Spiers, H. J. (2015). Hippocampal place cells construct reward related sequences through unexplored space. Elife



Javadi, A. H., & Spiers, H. J. (2015). Neuroscience: teleporting mind into body and space. Current Biology



Brunec, I. K., Chadwick, M. J., Javadi, A. H., Guo, L., Malcolm, C. P., & Spiers, H. J. (2015). Chronologically organized structure in autobiographical memory search. Frontiers in psychology



Spiers, H. J., & Gilbert, S. J. (2015). Solving the detour problem in navigation: a model of prefrontal and hippocampal interactions. Frontiers in human neuroscience



Spiers, H. J., & Barry, C. (2015). Neural systems supporting navigation. Current Opinion in Behavioral Sciences



Chadwick, M. J., Jolly, A. E., Amos, D. P., Hassabis, D., & Spiers, H. J. (2015). A goal direction signal in the human entorhinal/subicular region. Current Biology



Dalton, R. C., Hoelscher, C., & Spiers, H. J. (2015). Navigating complex buildings: Cognition, neuroscience and architectural design. Studying visual and spatial reasoning for design creativity


Javadi, A. H., Brunec, I. K., Walsh, V., Penny, W. D., & Spiers, H. J. (2014). Transcranial electrical brain stimulation modulates neuronal tuning curves in perception of numerosity and duration. Neuroimage



Chadwick, M. J., & Spiers, H. J. (2014). A local anchor for the brain's compass. Nature neuroscience



Howard, L. R., Javadi, A. H., Yu, Y., Mill, R. D., Morrison, L. C., Knight, R., Loftus, M. M., Staskute, L., & Spiers, H. J. (2014). The hippocampus and entorhinal cortex encode the path and Euclidean distances to goals during navigation. Current Biology



Spiers, H. J., & Bendor, D. (2014). Enhance, delete, incept: Manipulating hippocampus-dependent memories. Brain research bulletin



Spiers, H. J., Hayman, R. M., Jovalekic, A., Marozzi, E., & Jeffery, K. J. (2013). Place field repetition and purely local remapping in a multicompartment environment. Cerebral Cortex



Howard, L. R., Kumaran, D., Ólafsdóttir, H. F., & Spiers, H. J. (2013). Dissociation between dorsal and ventral posterior parietal cortical responses to incidental changes in natural scenes. PLoS One



Zisch, F., Gage, S., & Spiers, H. (2013). Navigating the Museum. The multisensory museum: cross-disciplinary perspectives on touch, sound, smell, memory, and space



Spiers, H. (2012). Hippocampal Formation. Encyclopedia of Human Behavior.



Howard, L. R., Kumaran, D., Ólafsdóttir, H. F., & Spiers, H. J. (2011). Double dissociation between hippocampal and parahippocampal responses to object–background context and scene novelty. Journal of Neuroscience.



Woollett, K., Spiers, H. J., & Maguire, E. A. (2009). Talent in the taxi: a model system for exploring expertise. Philosophical Transactions of the Royal Society B: Biological Sciences.



Spiers, H. J., & Maguire, E. A. (2008). The dynamic nature of cognition during wayfinding. Journal of Environmental Psychology.



Spiers, H. J. (2008). Keeping the goal in mind: Prefrontal contributions to spatial navigation. Neuropsychologia.



Kumaran, D., Hassabis, D., Spiers, H. J., Vann, S. D., Vargha-Khadem, F., & Maguire, E. A. (2007). Impaired spatial and non-spatial configural learning in patients with hippocampal pathology. Neuropsychologia.



Spiers, H. J., & Maguire, E. A. (2007). The neuroscience of remote spatial memory: a tale of two cities. Neuroscience.



Spiers, H. J., & Maguire, E. A. (2007). Decoding human brain activity during real-world experiences. Trends in cognitive sciences.



Spiers, H. J., & Maguire, E. A. (2007). A navigational guidance system in the human brain. Hippocampus.



Spiers, H. J., & Maguire, E. A. (2007). Neural substrates of driving behaviour. Neuroimage.



Spiers, H. J., & Maguire, E. A. (2006). Spontaneous mentalizing during an interactive real world task: an fMRI study. Neuropsychologia.



Maguire, E. A., Woollett, K., & Spiers, H. J. (2006). London taxi drivers and bus drivers: a structural MRI and neuropsychological analysis. Hippocampus.



Maguire, E. A., Nannery, R., & Spiers, H. J. (2006). Navigation around London by a taxi driver with bilateral hippocampal lesions. Brain.



Spiers, H. J., & Maguire, E. A. (2006). Thoughts, behaviour, and brain dynamics during navigation in the real world. Neuroimage.



Trinkler, I., King, J., Spiers, H. J., & Burgess, N. (2006). Part or parcel? Contextual binding of events in episodic memory. Handbook of binding and memory: Perspectives from cognitive neuroscience.



King, J. A., Hartley, T., Spiers, H. J., Maguire, E. A., & Burgess, N. (2005). Anterior prefrontal involvement in episodic retrieval reflects contextual interference. Neuroimage.



Lee, A. C., Buckley, M. J., Pegman, S. J., Spiers, H., Scahill, V. L., Gaffan, D., ... & Graham, K. S. (2005). Specialization in the medial temporal lobe for processing of objects and scenes. Hippocampus.



Burgess, N., Spiers, H. J., & Paleologou, E. (2004). Orientational manoeuvres in the dark: dissociating allocentric and egocentric influences on spatial memory. Cognition.



Spiers, H. J., & Maguire, E. A. (2004). A 'landmark' study on the neural basis of navigation. Nature Neuroscience.



Simons, J. S., & Spiers, H. J. (2003). Prefrontal and medial temporal lobe interactions in long-term memory. Nature reviews neuroscience.



Hartley, T., Maguire, E. A., Spiers, H. J., & Burgess, N. (2003). The well-worn route and the path less traveled: distinct neural bases of route following and wayfinding in humans. Neuron.



Maguire, E. A., Spiers, H. J., Good, C. D., Hartley, T., Frackowiak, R. S., & Burgess, N. (2003). Navigation expertise and the human hippocampus: a structural brain imaging analysis. Hippocampus.



Worsley, C. L., Recce, M., Spiers, H. J., Marley, J., Polkey, C. E., & Morris, R. G. (2001). Path integration following temporal lobectomy in humans. Neuropsychologia.



Spiers, H. J., Burgess, N., Maguire, E. A., Baxendale, S. A., Hartley, T., Thompson, P. J., & O'keefe, J. (2001). Unilateral temporal lobectomy patients show lateralized topographical and episodic memory deficits in a virtual town. Brain.



Burgess, N., Maguire, E. A., Spiers, H. J., & O'Keefe, J. (2001). A temporoparietal and prefrontal network for retrieving the spatial context of lifelike events. Neuroimage.



Spiers, H. J., Burgess, N., Hartley, T., Vargha‐Khadem, F., & O'Keefe, J. (2001). Bilateral hippocampal pathology impairs topographical and episodic memory but not visual pattern matching. Hippocampus.

Spiers, H. J., Maguire, E. A., & Burgess, N. (2001). Hippocampal amnesia. Neurocase.